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==In the Media==
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Dr. Banerjee and team received recognition for their work in dementia at the Women in Science special issue from UK based magazine Research Features: https://researchfeatures.com/2018/03/07/managing-dementia-through-a-multisensory-smart-phone-application-to-support-ageing-in-place/
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Date: 12/13/18 in Wright State news: http://webapp2.wright.edu/web1/newsroom/2017/12/13/special-care/
 +
 +
On November 8th, 2017, Miami Valley's Chapter of Alzheimer's Association hosted a Science Night called "Assessing Caregiver Stress and Burnout." For more details: https://alzdayton.wordpress.com/2017/09/25/science-night-assessing-caregiver-stress-and-burnout/
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==Motivation and Background==
 
==Motivation and Background==
More than 25 million people in the U.S. are diagnosed with asthma, out of which 7 million are children [1]. Asthma related healthcare costs alone are around $50 billion a year [2]. Current reactive healthcare costs more than 17% of GDP in the US [3, 4]. Specifically, with the current reactive care for asthma, there were 155,000 hospital admissions and 593,000 ER visits in 2006 [16]. It is estimated that, by 2025, over 400 million people will be affected by asthma worldwide. With increasing adoption of mobile devices and low-cost sensors, an unprecedented amount of data is being collected by people [5]. This data collection has exacerbated the problem of understanding the data and making sense of it. In this project, we explore the role of knowledge empowered algorithms in making sense of this data deluge in the context of asthma assessment and management.
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Alzheimer’s disease affects more than 5 million people claiming over 500,000 Americans annually [1]. As the sixth leading cause of death in Americans [1], its management is challenging. Current reactive healthcare costs more than 17% of GDP in the US [3, 4]. Alzheimer’s related healthcare costs alone are around $150 billion a year to Medicare and Medicaid [1]. To add to the challenge, dementia is an umbrella term that encompasses various forms of the disease such as Alzheimer’s disease, vascular dementia, and Huntington’s disease, to name a few [2]. Not only are the healthcare costs associated with dementia staggering, but the impact on the caregivers is also a critical challenge; in 2013, 15.5 million family and friends provided 17.7 billion hours of unpaid care to those with Alzheimer's and other forms of dementia – care valued at $220.2 billion [1]. With the exponential rise of the older population due to the baby boomers, the number of people with Alzheimer’s disease (the most prevalent form of dementia) is estimated to reach around 13.8 million [1,6]. This creates the strong need for unobtrusive sensing modalities that can help monitor people with dementia and support caregivers.
  
==Asthma: Challenges and Opportunities==
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==Dementia: Challenges and Opportunities==
Asthma is a good example of a problem that spans Physical-Cyber-Social ([[PCS]]) systems. The health signals related to asthma spans Physical (environmental), Cyber (CDC reports), and Social (asthma/symptom reports on social media) modalities. Specifically, for asthma, we group health signals  as personal (wheezing level, exhaled Nitric Oxide), population (asthma reports on social media), and public health signals (CDC asthma reports).
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With increasing adoption of mobile devices and low-cost sensors, an unprecedented amount of data is being collected [5]. However, in the context of dementia, it is challenging to convert this huge amount of data into actionable information that can: a) help detect behavioral changes in an individual with dementia and b) provide relevant information to the clinician supporting them in treating chronic illness. In our previous work, we derived actionable information from physical and physiological data collected from children diagnosed with asthma. We have developed kHealth kit [9, 28] a semantics-enabled smart mobile application with sensors, to capture observations from machine sensors (quantitative) and people (qualitative) in the domain of asthma [30]. We also have active clinical collaborations to investigate and evaluate the use of kHealth technology for reducing readmission of GI (gastrointestinal) and ADHF (acute decompensated heart failure) patients after their discharge from the hospital.
 +
<!-- [[File:asthma-health-signals.png | Asthma health signals spanning personal, public, and population level observations |600px]] -->
  
[[File:asthma-health-signals.png | Asthma health signals spanning personal, public, and population level observations |600px]]
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==CAST ( Caregiver Assessment Using Smart Gaming Technology)==
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The aim of this study is to detect changes in behavior (agitation, depression, and apathy, see here) and activity patterns of patients with dementia by using a combination of wearable and environmental sensors using a mobile platform. Detecting these behavior changes will result in a deeper understanding of the causes of mood and behavioral changes. This will involve detecting fluctuations in sleep patterns and evaluating the effects on stress using standard clinical methods. This can help predict mood events, which in turn can help alert clinicians for early intervention.
 +
The study will revolve around 10-20 dyads, each comprising a person with dementia (PwD) and his or her main caregiver (Cg). The person with dementia and caregiver must live in the same house or apartment. Sensors will be monitoring the sleep patterns of the patient as well as activity patterns using wearable sensors like the Jawbone UP24 to track parameters like number of steps, location, gait speed as well as wearable garments such as the Sensoria socks for an additional modality to measure gait parameters including speed, cadence, step count, etc. Environmental sensors like the Sense can be used to detect the activity trends. The data can be collected via Bluetooth and processed using an Android-based smartphone. Any abnormal changes in these patterns can then be validated using physical tests like TUG (obtained from the clinician), as well as cognitive tests like the Zarit Burden Interview (obtained from the caregiver). In addition, the effects of psychoactive medications for behavioral disturbances in patients will be associated with changes in their sleep and daily movements. This can provide long-term benefit to patients with dementia to monitor cognitive behavior as well as enable early intervention using ubiquitous sensors in an affordable and non-invasive manner.
  
==kHealth for Dementia==
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[[File:Dementia Current 5-9-2017.png | kHealth kit for Asthma |600px]]
We tackle this important problem by a combination of active and passive sensing. Active sensing involves the patient in the loop (obtrusive) while the passive sensing does not involve patient involvement (unobtrusive). Using a novel approach of utilizes low-cost sensors for continuous monitoring (active and passive sensing), we propose to develop algorithms that can take this multi-modal data and translate them to practical and actionable information for asthma patients and their healthcare provider. Specifically, provide information on asthma control level based on symptoms and their severity, asthma triggers and early alerts for increasing asthma symptoms.  
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<br/>Figure 1. The kHealth Dementia application will measure physiological signals from the person with dementia as well as the caregiver to provide a deeper understanding of the behavior changes contributing to dementia.
  
[[File:khealth-asthma-kit.png | kHealth kit for Asthma |600px]]
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==Current Team Members==
 
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==kHealth Observations==
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Asthma is a multi-faceted problem and we propose a holistic solution for <br/>
 
Asthma is a multi-faceted problem and we propose a holistic solution for <br/>
 
<b>Personal</b><br/>
 
<b>Personal</b><br/>
Physiological: Wheezometer [6], Nitric Oxide [7], Accelerometer, Microphone, Contextual Questions <br/>
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//Physiological: Wheezometer [6], Nitric Oxide [7], Accelerometer, Microphone, Contextual Questions <br/>
 
Environmental: Sensordrone [8], Dust Sensor [9], Location<br/>
 
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Everyaware [11], AirQuality Egg [12], Allergy Alerts [13,14], Social Observations (e.g., tweets), Air Quality Index[15]<br/>
 
Everyaware [11], AirQuality Egg [12], Allergy Alerts [13,14], Social Observations (e.g., tweets), Air Quality Index[15]<br/>
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==Preliminary Data Analysis==
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<b>Faculty:</b> Dr. Tanvi Banerjee (CECS, Kno.e.sis, Wright State University), Dr. Jennifer Hughes (Social Work, Wright State University)<br/>
kHealth kit could be used to collect observations (both sensor and patients questionnaire response) in the patient home environment (which was never accessible in a quantitative form to doctors). These observations when collected based on expert guidance, prove valuable for clinical decision support. These observations when interpreted by a doctor, lead to some interesting insights: <br/>
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<b>Mentors:</b> Dr. Larry Lawhorne (Geriatrics, Boonshoft School of Medicine, Wright State University), Dr. Amit Sheth (CECS, Kno.e.sis, Wright State University), Dr. Matthew Peterson (Geriatrics, Boonshoft School of Medicine, Wright State University, Dr. T. K. Prasad (CECS, Kno.e.sis, Wright State University)<br/>
*Medication (Albuterol) use possibly leading to decreasing exhaled Nitric Oxide
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<b>PhD Students:</b> Reza Sadeghi (Computer Science)<br/>
[[File:khealth-asthma-1.png | 400px | kHealth kit for Asthma ]] <br/>
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<b>Graduate Students:</b> Garrett Goodman (Computer Science), Morgan Freeman (Social Work), Joanna Meyer (Social Work), Brad Schneider (Computer Science)<br/>
*Activity limitation is likely related to high exhaled Nitric Oxide
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<b>Undergraduate Students:</b> Abby Edwards (Psychology), Alexandrea Oliver (Computer Science)
[[File:khealth-asthma-2.png | 400px | kHealth kit for Asthma ]] <br/>
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*Low exhaled Nitric Oxide observed with absence of coughing
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[[File:khealth-asthma-3.png | 400px | kHealth kit for Asthma ]] <br/>
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*Activity limitation observed with high pollen activity 
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[[File:khealth-asthma-4.png | 400px | kHealth kit for Asthma ]] <br/>
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<br/>
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THESE PRELIMINARY FINDINGS NEED TO BE VALIDATED IN LARGER STUDIES
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===Dataset Size===
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[[File:DaSH_Group_Picture2.jpg]]
We collect observations from three sensors (temperature, humidity, Carbon monoxide) on Sensordrone at the rate of 1 Hz (1 observation / second). Nitric Oxide observations  from the NODE sensor are collected at the rate of 2 observations / day. Patients answer a questionnaire which has 5 questions resulting in 5 observations / day. For a single patient, we collect over 250,000 observations / day. In our study of three patients, we have collected over 9 million data points.
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==IRB==
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==Funding==
Dayton Children's Hospital Institutional Review Board (IRB) approved the pilot study in October 2013 which began enrolling pediatric patients and their parents to use the kHealth kit for Asthma. IRB continuation was approved in October 2014. Please contact Prof. Amit Sheth  [amit at knoesis.org] or Dr. Shalini Forbis [ForbisS at childrensdayton.org]  to obtain the exact copy of IRB.
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This project is sponsored by the [https://www.nih.gov/ National National Institutes of Health (NIH)] Grant No. 1K01LM012439 to the [http://knoesis.org/ Ohio Center of Excellence in Knowledge-enabled Computing (Kno.e.sis)titled: '''Managing Dementia through a Multisensory Smart Phone Application to Support Aging in Place.''' Any opinions, findings, conclusions or recommendations expressed in this material are those of the investigator(s) and do not necessarily reflect the views of the National Institutes of Health. <br />
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==CAST app Description==
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Presented at NASA Ohio Space Grant Consortium, 2018 - Alexandrea Oliver.<br/>
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[[File:CAST_app_Description.png| CAST app description |200px | link=https://drive.google.com/open?id=1HaPRBJVV6vfUTjCBAGYbSxcSByamPq9w]]
  
 
==kHealth User Manual==
 
==kHealth User Manual==
[[File:K-Health_Asthma_User_Guide.png| kHealth Asthma user guide |150px | link=http://sonicbanana.cs.wright.edu/k-health/docs/kHealth-AsthmaUserManual-resized_2014_11_24_18_12_43_961.pdf]]
 
  
==kHealth Video Introduction==
 
{{#ev:youtube|PuQ5F2uVYjM|400|left|kHealth Asthma Application Overview}}
 
  
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[[File:khealthdementiaman.png| kHealth dementia user guide |200px | link=https://drive.google.com/open?id=0B-2OiKiC7xkLVEpfbWs4QVFOZlk]]
  
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==kHealth Vision==
 
{{#ev:youtube|R-LFcQtd1bs|400|left|Turning information into meaning: Dr. Amit Sheth}}
 
 
 
Digital health and mobile health applications are benefitting from semantic web research from Wright State's Ohio Center of Excellence in Knowledge-Enabled Computing (Kno.e.sis). Director of Kno.e.sis and Professor of Computer Science and Engineering Dr. Amit Sheth describes development of mobile health applications with sensor technology to monitor patient health, mobile computational support, and clear feedback to the patient and physician.
 
 
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==Related Talks and Presentations==
 
==Related Talks and Presentations==
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==References==
 
[1] Alzheimer’s Association description of Alzheimer’s statistics, Available online at:
 
  
http://www.alz.org/alzheimers_disease_facts_and_figures.asp
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[[File:Title.png| kHealth dementia paper |400px|433px | link=https://drive.google.com/open?id=0By39GGXx-P9NR29MeUx3b19abDQ]]
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<html>
  
#quickFacts
 
[2] Dementia related facts, Available online at: http://www.cdc.gov/mentalhealth/basics/mental-
 
illness/dementia.htm
 
  
[3] D. A. Squires, “The U.S. Health System in Perspective: A Comparison of Twelve Industrialized Nations,” June 2011, Available online at: http://bit.ly/oZwhFZ
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<iframe src="//www.slideshare.net/slideshow/embed_code/key/4gZ63PC10GwH9V" width="425" height="355" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" style="border:1px solid #CCC; border-width:1px; margin-bottom:5px; max-width: 100%;" allowfullscreen> </iframe> <div style="margin-bottom:5px"> <strong> <a href="//www.slideshare.net/knoesis/2015-presentation-hims" title="Evaluating a Potential Commercial Tool for Healthcare Application for People with Dementia " target="_blank">Evaluating a Potential Commercial Tool for Healthcare Application for People with Dementia </a> </strong> from <strong><a href="//www.slideshare.net/knoesis" target="_blank">Kno.e.sis Center, Wright State University</a></strong> </div></html>
  
[4] Health Costs: How the U.S. Compares With Other Countries, Available online at:
 
http://www.pbs.org/newshour/rundown/2012/10/health-costs-how-the-us-compares-with-other-countries.html
 
  
[5] Quantified Self http://quantifiedself.com/
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==Project's Papers==
[6] G. K. Vincent, V. A. Velkof, “The next four decades: The older population in the United States: 2010 to 2050.” Washington, D.C.: U.S. Census Bureau; 2010.
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[1] T. Banerjee, P. Anantharam, W. L. Romine, and L. W. Lawhorne, "Evaluating a Potential Commercial Tool for Healthcare Application for People with Dementia," <i>Wright State University CORE Scholar Kno.e.sis Publications</i>, 2015.
  
[7] Hexoskin. www.hexoskin.com
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[2] J. C. Hughes, T. Banerjee, G. Goodman, and L. W. Lawhorne, “A Preliminary Qualitative Analysis on the Feasibility of Using Gaming Technology in Caregiver Assessment," <i>Journal of Technology in Human Services</i>, vol. 35, no. 3, pp. 183-198, Mar. 2017.
  
[8] A. Pasolini, "Sensor-packed Hexoskin shirt measures performance in real time". Available at:
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[3] T. Banerjee, M. Peterson, Q. Oliver, A. Froehle, and L. W. Lawhorne, "Validating a Commercial Device for Continuous Activity Measurement in the Older Adult Population for Dementia Management," <i>Smart Health</i>, 2017.
http://www.gizmag.com/hexoskin-sensor-t-shirt-body-metrics/29098/ Gizmag. September 19, 2013.
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[9] kHealth: A knowledge-enabled semantic platform to enhance decision making and improve health, fitness, and well-being, Available online at: http://knoesis.org/projects/khealth (Accessed May 27, 2013).
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[4] R. Sadeghi, T. Banerjee, J. C. Hughes, G. Goodman, and L. W. Lawhorne, “Predicting sleep quality of
 +
dementia caregivers using physiological signals”, Submitted to <i>Computers in Biology and Medicine</i>, 2019.
  
[10] V. Santhisagar, T. Ioannis, B. Diane, J. C. Faquir, P. Fotios, "Emerging synergy between nanotechnology and implantable biosensors: A review." Biosensors and Bioelectronics 25.7: 1553-1565, 2010.
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==References==
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[1] Alzheimer’s Association description of Alzheimer’s statistics, Available online at: http://www.alz.org/alzheimers_disease_facts_and_figures.asp #quickFacts
  
[11] J. S. Karlsson, U. Wiklund, L. Berglin, N. Östlund, M. Karlsson, T. Bäcklund, & L. Sandsjö, “Wireless monitoring of heart rate and electromyographic signals using a smart T-shirt.” In Proceedings of International Workshop on Wearable Micro and Nanosystems for Personalised Health, 2008.
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[2] Dementia related facts, Available online at: http://www.cdc.gov/mentalhealth/basics/mental-illness/dementia.htm
  
[12] M. Chan, E. Campo, D. Estève, & J. Y. Fourniols, "Smart homes—current features and future perspectives. " Maturitas, 64(2), 90-97, 2009.
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[3] D. A. Squires, “The U.S. Health System in Perspective: A Comparison of Twelve Industrialized Nations,” June 2011, Available online at: http://bit.ly/oZwhFZ
  
[13] E. Topol, “The creative destruction of medicine: How the digital revolution will create better health care.” Basic Books (AZ), 2012.
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[4] Health Costs: How the U.S. Compares With Other Countries, Available online at: http://www.pbs.org/newshour/rundown/2012/10/health-costs-how-the-us-compares-with-other-countries.html
  
[14] T. Banerjee, M. Skubic, J. M. Keller & C. C. Abbott, "Sit-To-Stand Measurement For In Home Monitoring Using Voxel Analysis," IEEE Journal of Biomedical and Health Informatics, 18(4):1502-1509, 2014.
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[5] Quantified Self http://quantifiedself.com/
  
[15] T. Banerjee, M. Rantz, M. Li, M. Popescu, E. Stone & M. Skubic, "Monitoring Hospital Rooms for Safety Using Depth Images," Proceedings, AAAI Fall Symposium Series - AI for Gerontechnology, Washington DC, November 2-4, 2012.
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[6] G. K. Vincent, V. A. Velkof, “The next four decades: The older population in the United States: 2010 to 2050.” Washington, D.C.: U.S. Census Bureau; 2010.
 
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[16] M. Gietzelt, K. H. Wolf, M. Kohlmann, M. Marschollek, and R. Haux. "Measurement of Accelerometry-based Gait Parameters in People with and without Dementia in the Field." Methods Inf. Med 52, no. 4: 319-325, 2013.
+
 
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[17] E. Stone & M. Skubic, "Evaluation of an Inexpensive Depth Camera for In-Home Gait Assessment," Journal of Ambient Intelligence and Smart Environments, 3(4):349-361, 2011.
+
 
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[18] A. L. Bleda, R. Maestre, A. J. Jara, & A. G. Skarmeta, “Ambient Assisted Living Tools for a Sustanaible Aging Society.” In Resource Management in Mobile Computing Environments pp. 193-220. Springer International Publishing, 2014.
+
 
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[19] J. L. Cummings, “The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients.” Neurology 48 (Supple 6): S10-S16,1997.
+
 
+
[20] W. E. Haley, E. G. Levine, S. L. Brown, and A. A. Bartolucci. "Stress, appraisal, coping, and social support as predictors of adaptational outcome among dementia caregivers." Psychology and aging 2, no. 4: 323, 1987.
+
 
+
[21] Fitbit sensor. www.fitbit.com
+
 
+
[22] S. H. Zarit, K. E Reever, J. Bach-Peterson, “Relatives of the impaired elderly: correlates of feelings of burden.” Gerontologist. 20:649–55, 1980.
+
 
+
[23] D. Tobon Vallejo, T. Falk, M. Maier, "MS-QI: A Modulation Spectrum-Based ECG Quality Index for Telehealth Applications," Biomedical Engineering, IEEE Transactions on, 2015.
+
 
+
[24] R. T. Warne, "A primer on multivariate analysis of variance (MANOVA) for behavioral scientists". Practical Assessment, Research & Evaluation 19 (17): 1–10, 2014.
+
 
+
[25] K. V. Mardia, J. T. Kent, J. M. Bibby, “Multivariate Analysis.” Academic Press, 1979.
+
 
+
[26] J. Schmid Jr., "The Relationship between the Coefficient of Correlation and the Angle Included between Regression Lines". The Journal of Educational Research 41 (4), 1947.
+
  
[27] Hexoskin data validation. Available at: https://cdn.shopify.com/s/files/1/0284/7802/files/CSEP_Hexo skin_Poster_-_University_of_Waterloo.pdf?11148
+
[7] kHealth: A knowledge-enabled semantic platform to enhance decision making and improve health, fitness, and well-being, Available online at: http://knoesis.org/projects/khealth (Accessed May 27, 2013).
  
[28] A. Sheth, P. Anantharam, K. Thirunarayan, “kHealth: Proactive Personalized Actionable Information for Better Healthcare,” Workshop on Personal Data Analytics in the Internet of Things (PDA@IOT 2014), collocated at VLDB 2014, Hangzhou, China, September 5th 2014.
+
[8] A. Sheth, P. Anantharam, K. Thirunarayan, “kHealth: Proactive Personalized Actionable Information for Better Healthcare,” Workshop on Personal Data Analytics in the Internet of Things (PDA@IOT 2014), collocated at VLDB 2014, Hangzhou, China, September 5th 2014.
  
[29] C.R. Rao. “Estimation of variance and covariance components in linear models.” Journal of the American Statistical Association, 67(337), 112-115, 1972.
+
[9] P. Anantharam, T. Banerjee, A. Sheth, K. Thirunarayan, S. Marupudi, V. Sridharan, S. G. Forbis, "Knowledge-driven Personalized Contextual mHealth Service for Asthma Management in Children", IEEE 4th International Conference on Mobile Services, June 27 - July 2, 2015, New York, USA
  
[30] P. Anantharam, T. Banerjee, A. Sheth, K. Thirunarayan, S. Marupudi, V. Sridharan, S. G. Forbis, "Knowledge-driven
+
==Related kHealth Projects==
 +
*[http://knoesis.org/projects/khealth kHealth overview with example of ADHF]
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*[http://wiki.knoesis.org/index.php/Asthma Asthma]
 +
*kHealth for reducing liver cirrhosis readmission (to come)

Latest revision as of 21:07, 28 February 2019

In the Media

Dr. Banerjee and team received recognition for their work in dementia at the Women in Science special issue from UK based magazine Research Features: https://researchfeatures.com/2018/03/07/managing-dementia-through-a-multisensory-smart-phone-application-to-support-ageing-in-place/

Date: 12/13/18 in Wright State news: http://webapp2.wright.edu/web1/newsroom/2017/12/13/special-care/

On November 8th, 2017, Miami Valley's Chapter of Alzheimer's Association hosted a Science Night called "Assessing Caregiver Stress and Burnout." For more details: https://alzdayton.wordpress.com/2017/09/25/science-night-assessing-caregiver-stress-and-burnout/

Motivation and Background

Alzheimer’s disease affects more than 5 million people claiming over 500,000 Americans annually [1]. As the sixth leading cause of death in Americans [1], its management is challenging. Current reactive healthcare costs more than 17% of GDP in the US [3, 4]. Alzheimer’s related healthcare costs alone are around $150 billion a year to Medicare and Medicaid [1]. To add to the challenge, dementia is an umbrella term that encompasses various forms of the disease such as Alzheimer’s disease, vascular dementia, and Huntington’s disease, to name a few [2]. Not only are the healthcare costs associated with dementia staggering, but the impact on the caregivers is also a critical challenge; in 2013, 15.5 million family and friends provided 17.7 billion hours of unpaid care to those with Alzheimer's and other forms of dementia – care valued at $220.2 billion [1]. With the exponential rise of the older population due to the baby boomers, the number of people with Alzheimer’s disease (the most prevalent form of dementia) is estimated to reach around 13.8 million [1,6]. This creates the strong need for unobtrusive sensing modalities that can help monitor people with dementia and support caregivers.

Dementia: Challenges and Opportunities

With increasing adoption of mobile devices and low-cost sensors, an unprecedented amount of data is being collected [5]. However, in the context of dementia, it is challenging to convert this huge amount of data into actionable information that can: a) help detect behavioral changes in an individual with dementia and b) provide relevant information to the clinician supporting them in treating chronic illness. In our previous work, we derived actionable information from physical and physiological data collected from children diagnosed with asthma. We have developed kHealth kit [9, 28] a semantics-enabled smart mobile application with sensors, to capture observations from machine sensors (quantitative) and people (qualitative) in the domain of asthma [30]. We also have active clinical collaborations to investigate and evaluate the use of kHealth technology for reducing readmission of GI (gastrointestinal) and ADHF (acute decompensated heart failure) patients after their discharge from the hospital.

CAST ( Caregiver Assessment Using Smart Gaming Technology)

The aim of this study is to detect changes in behavior (agitation, depression, and apathy, see here) and activity patterns of patients with dementia by using a combination of wearable and environmental sensors using a mobile platform. Detecting these behavior changes will result in a deeper understanding of the causes of mood and behavioral changes. This will involve detecting fluctuations in sleep patterns and evaluating the effects on stress using standard clinical methods. This can help predict mood events, which in turn can help alert clinicians for early intervention. The study will revolve around 10-20 dyads, each comprising a person with dementia (PwD) and his or her main caregiver (Cg). The person with dementia and caregiver must live in the same house or apartment. Sensors will be monitoring the sleep patterns of the patient as well as activity patterns using wearable sensors like the Jawbone UP24 to track parameters like number of steps, location, gait speed as well as wearable garments such as the Sensoria socks for an additional modality to measure gait parameters including speed, cadence, step count, etc. Environmental sensors like the Sense can be used to detect the activity trends. The data can be collected via Bluetooth and processed using an Android-based smartphone. Any abnormal changes in these patterns can then be validated using physical tests like TUG (obtained from the clinician), as well as cognitive tests like the Zarit Burden Interview (obtained from the caregiver). In addition, the effects of psychoactive medications for behavioral disturbances in patients will be associated with changes in their sleep and daily movements. This can provide long-term benefit to patients with dementia to monitor cognitive behavior as well as enable early intervention using ubiquitous sensors in an affordable and non-invasive manner.

kHealth kit for Asthma
Figure 1. The kHealth Dementia application will measure physiological signals from the person with dementia as well as the caregiver to provide a deeper understanding of the behavior changes contributing to dementia.

Current Team Members

Faculty: Dr. Tanvi Banerjee (CECS, Kno.e.sis, Wright State University), Dr. Jennifer Hughes (Social Work, Wright State University)
Mentors: Dr. Larry Lawhorne (Geriatrics, Boonshoft School of Medicine, Wright State University), Dr. Amit Sheth (CECS, Kno.e.sis, Wright State University), Dr. Matthew Peterson (Geriatrics, Boonshoft School of Medicine, Wright State University, Dr. T. K. Prasad (CECS, Kno.e.sis, Wright State University)
PhD Students: Reza Sadeghi (Computer Science)
Graduate Students: Garrett Goodman (Computer Science), Morgan Freeman (Social Work), Joanna Meyer (Social Work), Brad Schneider (Computer Science)
Undergraduate Students: Abby Edwards (Psychology), Alexandrea Oliver (Computer Science)

DaSH Group Picture2.jpg

Funding

This project is sponsored by the National National Institutes of Health (NIH) Grant No. 1K01LM012439 to the Ohio Center of Excellence in Knowledge-enabled Computing (Kno.e.sis) titled: Managing Dementia through a Multisensory Smart Phone Application to Support Aging in Place. Any opinions, findings, conclusions or recommendations expressed in this material are those of the investigator(s) and do not necessarily reflect the views of the National Institutes of Health.

CAST app Description

Presented at NASA Ohio Space Grant Consortium, 2018 - Alexandrea Oliver.
CAST app description

kHealth User Manual

kHealth dementia user guide


Related Talks and Presentations

kHealth dementia paper



Project's Papers

[1] T. Banerjee, P. Anantharam, W. L. Romine, and L. W. Lawhorne, "Evaluating a Potential Commercial Tool for Healthcare Application for People with Dementia," Wright State University CORE Scholar Kno.e.sis Publications, 2015.

[2] J. C. Hughes, T. Banerjee, G. Goodman, and L. W. Lawhorne, “A Preliminary Qualitative Analysis on the Feasibility of Using Gaming Technology in Caregiver Assessment," Journal of Technology in Human Services, vol. 35, no. 3, pp. 183-198, Mar. 2017.

[3] T. Banerjee, M. Peterson, Q. Oliver, A. Froehle, and L. W. Lawhorne, "Validating a Commercial Device for Continuous Activity Measurement in the Older Adult Population for Dementia Management," Smart Health, 2017.

[4] R. Sadeghi, T. Banerjee, J. C. Hughes, G. Goodman, and L. W. Lawhorne, “Predicting sleep quality of dementia caregivers using physiological signals”, Submitted to Computers in Biology and Medicine, 2019.

References

[1] Alzheimer’s Association description of Alzheimer’s statistics, Available online at: http://www.alz.org/alzheimers_disease_facts_and_figures.asp #quickFacts

[2] Dementia related facts, Available online at: http://www.cdc.gov/mentalhealth/basics/mental-illness/dementia.htm

[3] D. A. Squires, “The U.S. Health System in Perspective: A Comparison of Twelve Industrialized Nations,” June 2011, Available online at: http://bit.ly/oZwhFZ

[4] Health Costs: How the U.S. Compares With Other Countries, Available online at: http://www.pbs.org/newshour/rundown/2012/10/health-costs-how-the-us-compares-with-other-countries.html

[5] Quantified Self http://quantifiedself.com/

[6] G. K. Vincent, V. A. Velkof, “The next four decades: The older population in the United States: 2010 to 2050.” Washington, D.C.: U.S. Census Bureau; 2010.

[7] kHealth: A knowledge-enabled semantic platform to enhance decision making and improve health, fitness, and well-being, Available online at: http://knoesis.org/projects/khealth (Accessed May 27, 2013).

[8] A. Sheth, P. Anantharam, K. Thirunarayan, “kHealth: Proactive Personalized Actionable Information for Better Healthcare,” Workshop on Personal Data Analytics in the Internet of Things (PDA@IOT 2014), collocated at VLDB 2014, Hangzhou, China, September 5th 2014.

[9] P. Anantharam, T. Banerjee, A. Sheth, K. Thirunarayan, S. Marupudi, V. Sridharan, S. G. Forbis, "Knowledge-driven Personalized Contextual mHealth Service for Asthma Management in Children", IEEE 4th International Conference on Mobile Services, June 27 - July 2, 2015, New York, USA

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